“Genomic Homeopathy” proposal: use of auto-isotherapic of DNA as a modulator of gene expression in chronic diseases - RAMB - 2023

Teixeira MZ. “Genomic Homeopathy” proposal: use of auto-isotherapic of DNA as a modulator of gene expression in chronic diseases. Rev Assoc Med Bras. 2023; 69(1): 13-17.

Disponível em: https://pubmed.ncbi.nlm.nih.gov/36629657 / https://doi.org/10.1590/1806-9282.20221156 /

                      RAMB - Journal of The Brazilian Medical Association / Old Scielo / ResearchGate

Summary

The vitalist philosophical conception considers vital force dystonia as the primary cause of diseases, while the return to health status would occur by vital rebalancing. The homeopathic model expands understanding of the etiopathogenic dynamics, and also considers the manifestation of chronic miasmas (manifest psora) as a fundamental cause of chronic diseases in general, while health restoration would occur through modulating this miasmatic manifestation (latent psora). According to the biomedical etiopathogenic process, the primary cause of diseases is the expression of genes responsible for the respective physiological disorders, considering the manifestation of disease-promoting epigenetic alterations as a fundamental cause of chronic diseases in general. The return to health status would occur through modulating these epigenetic manifestations and consequent inhibition of pathological gene expression. Due to presenting similar characteristics and properties, we have suggested in recent studies the philosophical-scientific correlations between vital force and genome (exome plus epigenome) and between chronic miasms and disease-promoting epigenetic alterations, meaning that the genome would be the biological representation of organic vital force, and disease-promoting epigenetic alterations would be the biological representation of chronic miasms. The properties and functions of the telomere-telomerase complex expand understanding of the gene expression mechanism at the chromosome level (DNA molecule or genomic unit), and reiterate the philosophical-scientific correlations between the vital principle and the genome in view of its recognized role as a biomarker of cellular vitality, biological aging and the health-disease process. In this context, telomere length would indicate the organic vital force state and could be used in the diagnosis and prognosis of diseases according to the vitalist approach, expanding the spectrum and scope of classical homeopathic semiology. In accordance with these hypotheses, the isopathic use of auto-sarcode of DNA (auto-isotherapic of DNA) could act on the imbalance of the vital principle or genome and in the chronic miasmas or disease-promoting epigenetic alterations as homeopathic therapeutic modulator of gene expression in the management of chronic diseases.

Leituras Associadas:

Teixeira MZ. Telomere length: biological marker of cellular vitality, aging, and health-disease process. Rev Assoc Med Bras 2021; 67(2): 173-177. Disponível em

Teixeira MZ. Telomere and telomerase: biological markers of organic vital force state and homeopathic treatment effectiveness. Homeopathy 2021; 110(04): 283-291. Disponível em

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Teixeira MZ. Telómeros y telomerasa: marcadores biológico-genómicos de la vitalidad-actividad celular, de la longevidad-envejecimiento y del proceso salud-enfermedad. La Homeopatía de México 2020; 89(720): 12-17. Disponível em

Teixeira MZ. Telômeros e telomerase: marcadores biológicos e genômicos da vitalidade/atividade celular, da longevidade/envelhecimento e do processo saúde-doença. Disponível em

Teixeira MZ. Correlation between vitalism and genetics according to the paradigm of complexity. Homeopathy 2020; 109(1): 30-36. Disponível em

Teixeira MZ. Isopathic use of auto-sarcode of DNA as anti-miasmatic homeopathic medicine and modulator of gene expression? Homeopathy 2019; 108(2): 139-147. Disponível em

Teixeira MZ. Interconexão entre saúde, espiritualidade e religiosidade: importância do ensino, da pesquisa e da assistência na educação médica. Revista de Medicina (São Paulo) 2020; 99(2): 134-147. Disponível em

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Project: 

Genomic Homeopathy: isopathic use of auto-sarcode of DNA (auto-isotherapic of DNA) as homeopathic therapeutic modulator of gene expression in the management of chronic diseases. Disponível em

Comentário sobre a publicação:

Dear Dr. Teixeira,
Great work and scientific thoughts! Also special thanks for citing our original related works as well.
Best wishes and regards.
Anisur R. Khuda Bukhsh
Retd. Professor Emeritus of UGC,
Deptt. of Zoology, University of Kalyani,
Kalyani-741235, India